Pantoprazole Magnesium Dihydrate: Molecular Formula, CAS Number & Properties

Pantoprazole Magnesium Dihydrate is an important pharmaceutical compound widely used in the development and formulation of proton pump inhibitor (PPI) medications. It is commonly utilized in pharmaceutical research, analytical studies, API development, and quality control applications.

This compound is a magnesium salt form of pantoprazole and is known for its stability and effectiveness in acid-suppressing formulations. Pharmaceutical manufacturers and analytical laboratories often use high-purity Pantoprazole Magnesium Dihydrate reference materials during analytical method development, impurity profiling, and stability testing.

Companies such as Chemicea provide high-quality pharmaceutical reference standards, impurity standards, API materials, and analytical compounds for pharmaceutical research and quality control applications.

What Is Pantoprazole Magnesium Dihydrate?

Pantoprazole Magnesium Dihydrate is a proton pump inhibitor (PPI) compound used in pharmaceutical formulations designed to reduce stomach acid production.

It belongs to the benzimidazole class of compounds and is commonly associated with gastrointestinal therapeutic research.

The magnesium salt form improves:

Stability

Formulation performance

Pharmaceutical processing properties

Molecular Formula of Pantoprazole Magnesium Dihydrate

The molecular formula of Pantoprazole Magnesium Dihydrate is:

C32​ H28 ​F4 ​Mg N6 ​O8​ S2​ ⋅ 2H2​O

This formula represents:

• Pantoprazole magnesium salt

• Two water molecules (dihydrate form)

The dihydrate structure contributes to the compound’s physical and chemical stability.

CAS Number of Pantoprazole Magnesium Dihydrate

The CAS Number is a unique chemical identifier used internationally for chemical substances.

Pantoprazole Magnesium Dihydrate is commonly identified using its specific CAS registry number in:

Pharmaceutical databases

Regulatory documentation

Chemical inventories

Analytical reports

CAS numbers help avoid confusion between:

Salt forms

Hydrates

Isomers

Related compounds

Key Chemical Properties

Pantoprazole Magnesium Dihydrate possesses several important pharmaceutical and analytical properties.

Property	Details
Compound Type	Proton Pump Inhibitor (PPI)
Chemical Form	Magnesium Salt Dihydrate
Appearance	White to off-white powder
Solubility	Slightly soluble in water
Stability	Improved stability compared to some free base forms
Usage	Pharmaceutical research and analytical applications

Importance in Pharmaceutical Research

Pantoprazole Magnesium Dihydrate is widely used in:

API development

Formulation studies

Analytical method development

Stability testing

Pharmaceutical quality control

Pharmaceutical companies require high-purity reference materials for accurate analytical testing and reproducibility.

Role in Analytical Method Development

Analytical laboratories use Pantoprazole Magnesium Dihydrate during:

HPLC analysis

Assay testing

Stability studies

Dissolution testing

Impurity profiling

Accurate reference standards help ensure:

Reliable quantification

Proper peak identification

Method reproducibility

Importance in Stability Studies

Pantoprazole compounds can be sensitive to:

Moisture

Temperature

Acidic conditions

Oxidative degradation

The magnesium dihydrate form helps improve formulation stability during pharmaceutical development and storage studies.

Reference standards are essential for monitoring:

Degradation products

Stability-related impurities

Analytical consistency

Importance of Pharmaceutical Reference Standards

Reference standards are critical for:

Pharmaceutical quality control

Regulatory compliance

Method validation

Analytical accuracy

High-quality analytical standards improve:

Reproducibility

Sensitivity

Data reliability

Companies like Chemicea provide pharmaceutical reference materials used in analytical laboratories and pharmaceutical research applications.

Related Pharmaceutical Impurity Standards

Pantoprazole-related analytical studies may also involve impurity and related compound analysis.

Relevant pharmaceutical impurity standards from your list include:

Ketoconazole EP Impurity A

Mirtazapine EP Impurity C

Donepezil EP Impurity G

Bisoprolol EP Impurity B

These standards are commonly used during:

HPLC method development

Impurity profiling

Stability-indicating methods

Pharmaceutical Applications

Pantoprazole Magnesium Dihydrate may be involved in:

API manufacturing

Research formulations

Dissolution studies

Stability analysis

Pharmaceutical analytical testing

High-purity analytical materials support accurate laboratory results.

Importance in HPLC and LC-MS Analysis

The compound is frequently analyzed using:

HPLC

UPLC

LC-MS/MS

These techniques help determine:

Purity

Assay value

Related substances

Degradation products

Analytical reference standards improve chromatographic accuracy and reproducibility.

Storage and Handling Considerations

Proper storage conditions are important to maintain:

Chemical integrity

Analytical purity

Stability

Pharmaceutical reference standards are typically stored:

In cool, dry conditions

Protected from light and moisture

In tightly sealed containers

Conclusion

Pantoprazole Magnesium Dihydrate is an important pharmaceutical compound widely used in analytical chemistry, API research, formulation development, and pharmaceutical quality control. Its improved stability and analytical relevance make it valuable for HPLC analysis, stability studies, and pharmaceutical method development.

High-quality reference standards are essential for accurate impurity profiling, analytical validation, and reproducible laboratory results.

Companies like Chemicea support pharmaceutical laboratories and researchers by providing API reference standards, impurity standards, intermediates, and analytical compounds for pharmaceutical research and quality control applications.